For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. In Canada - Call your doctor for medical advice about side effects. With IDA, you have low hemoglobin levels. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Its caused by your body not having enough iron, which is needed to make hemoglobin. There isnt a known interaction between Injectafer and alcohol. And these two doses need to be separated by at least 7 days. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. The insurance company will review the prior authorization request and decide if the drug will be covered. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). An iron infusion is a way to increase the body's iron levels quickly. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. You may report side effects to Health Canada at 1-866-234-2345. Phosphorus is an electrolyte that your body needs in order to make energy. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. intense abdominal pain. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Depending on your doctors instructions and You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Venofer treatment may be repeated if iron deficiency reoccurs. Injectafer can cause mild or serious side effects. However, be sure to take the dosage your doctor prescribes for you. As with all medications, the cost of Injectafer can vary. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. It may also cause nervousness, restlessness, and difficulty sleeping in some people. <> The following information describes dosages that are commonly used or recommended. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Can diet help improve depression symptoms? It is important to get each dose of this medication as scheduled. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. There are currently no generic forms of either drug. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Tell your doctor if you are pregnant or plan to become pregnant. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. Back pain. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. So you wont pick up this medication from a pharmacy. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Consult the product instructions and your pharmacist for storage details. It belongs to a class of medications called iron replacement products. But you kidneys need iron in order to make EPO. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Mild side effects of Injectafer can include:*. Injectafer contains the active drug ferric carboxymaltose. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Call your doctor for medical advice about side effects. Venofer pregnancy and breastfeeding warnings. Canada residents can call a provincial poison control center. An LSD comedown is when the mental and hallucinatory effects have worn . Its possible that after getting two doses of Injectafer, your anemia may go away completely. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. But for other people, their IDA returns after treatment with Injectafer. People with IDA have low blood levels of hemoglobin. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This includes your doctors, nurses, pharmacists, and dentists. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. For example: Say you weigh 105 pounds (about 48 kilograms). Both Injectafer and Venofer belong to a class of medications called iron replacement products. Your doctor will determine the best dosage to fit your needs. Injectafer isnt available in a generic form. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Understanding what thoseside effectsare can lead to a strategy to prevent them. Venofer is for use in adults and children at least 2 years old. 2. There are currently no generic forms of either drug. WebMD provides common contraindications for Venofer Vial. Review our medical disclaimer. * This is a partial list of mild side effects from Injectafer. Tell your doctor if you are taking iron supplements or other iron-based oral medications. If you notice other effects not listed above, contact your doctor or pharmacist. Your doctor will do laboratory tests to monitor your response. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). Any long-term side effects/dangers from iron infusions? A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. This is not a complete list of possible side effects. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Low iron saturation, or iron deficiency, has various possible causes. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. FG Trade/E+ sia Getty Images If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. If you think there has been an overdose, call your poison control center or get medical care right away. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. In the first group, some people continued taking iron by mouth, while other people took Injectafer. Copyright 1996-2023 Cerner Multum, Inc. I can't take oral supplements because they cause horrible debilitating Constipation. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as: This list is not complete. Boxed warnings alert doctors and patients about drug effects that may be dangerous. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Which tests can diagnose iron deficiency anemia? Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. Keep out of reach of children. Most of these side effects may go away within a few days or a couple of weeks. MNT is the registered trade mark of Healthline Media. You may need extra iron because of blood loss during kidney dialysis. Properly discard this product when it is expired or no longer needed. 2005 - 2023 WebMD LLC. Feraheme also comes as a liquid thats given by IV infusion. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. But for other people, doing so could lead to having too much iron in their body. generalized weakness. Examples of thisinclude: Not allside effectslast forever. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Call your doctor for instructions if you miss an appointment for your Venofer injection. Many patients with kidney disease cannot get enough iron from food and require injections. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). This is not a list of all drugs or health problems that interact with this medicine. This document does not contain all possible drug interactions. With IDA, you have low hemoglobin levels. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ Renal elimination is negligible. *Patients are calculated based on an estimated annual cumulative dose. Selected from data included with permission and copyrighted by First Databank, Inc. If either is present, do not use the liquid. Most people do not know how long theirside effectswill last until they go through them. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. A healthcare provider will give you this injection. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Brand-name medications usually cost more than generics. This is why family members often have the same issues with drugs as others in theirfamily. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. In clinical trials,. (A class of medications describes a group of drugs that work in the same way.). Pain, swelling, or redness at the injection site may occur. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. 2023 Medicine.com All rights reserved. With slow IV injection, the drug is given as a single, slow injection into your vein. % Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Its not known how common delayed allergic reaction might be in other people using Injectafer. Call your doctor for medical advice about side effects. Or your doctor may recommend that you change your eating habits to include more iron in your diet. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Many people believe they are suffering fromside effectsand may actually be suffering from anothermedical condition, such as havingdifficulty breathingorshortness of breath, which could be a heartattack. But the length of time that this may take varies from person to person. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. If you have symptoms of a low phosphorus level, call your doctor. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. One of the most commonly used tests to monitor IDA is the hemoglobin test. I was surprised too but the Dr said it definitely sounds like a reaction. (A class of medications describes a group of drugs that work in the same way.). Why is the range so wide? Do not start, stop, or change the dosage of any medicines without your doctor's approval. Be ready to tell or show what was taken, how much, and when it happened. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. You should always consult your doctor or another healthcare professional before taking any medication. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. After the infusion, you can drive yourself home and return to your usual activities. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). This includes people who: Usually, hypophosphatemia doesnt cause symptoms. other treatments you receive, you will need to go back for several treatments with Venofer. 2 0 obj Before using, check this product visually for particles or discoloration. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. . Some may be a better fit for you than others. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Its given by either intravenous (IV) infusion or slow IV injection. Iron infusion benefits. They can give you tips on how to deal with any side effects that may be bothersome. If you have a severe allergic reaction to Injectafer after youve left the medical facility where you received your dose of the drug, call your doctor right away. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Injectafer comes as a liquid solution inside vials. Last updated on Feb 20, 2023. What are the side effects of Venofer? Pain in your limbs. Side effectsare uncomfortable reactions to medications or drugs. Their medical staff can help you set up another time to receive your Injectafer dose. endobj With slow IV injection, the drug is given as a single, slow injection into your vein. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Tell all of your health care providers that you take Venofer. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. Injectafer contains the active drug ferric carboxymaltose. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Cardiovascular health: Insomnia linked to greater risk of heart attack. weakness. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. Do not exceed 1,500 mg of iron per dosing course. Otherwise, call a poison control center right away. These side effects can range from being mild to severe. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. Back pain. They can tell you about other medications that may work well for you. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. Orofer S 50 Injection 1 Injection in 1 Packet 147. Infusion times range from less than 20 minutes to up to 4 hours. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Learn about the causes, symptoms, diagnosis, and treatment of this. <> However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Evenbirth controlcan lead to severeside effectslike bloodclots. Learn more about the types of tests and treatment. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. These are not all of the side effects that may occur. Here's some detail on certain side effects this drug may cause. This is not a complete list of side effects and others may occur. Precautions. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. In one study, people were given either Injectafer or an iron replacement drug called Venofer. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
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